PHARMACEUTICAL COMPOSITION COMPRISING BOTH STREPTONIGRIN AND ANTI-CANCER AGENT FOR PREVENTING OR TREATING CANCER

The present invention relates to a pharmaceutical composition or an adjuvant anti-cancer agent for preventing or treating cancer comprising both streptonigrin and and one or more anti-cancer agents selected from the group consisting of cisplatin, gemcitabine, and paclitaxel. Additionally, the presen...

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Bibliographic Details
Main Authors HEO, Kyun, LIM, Myong Cheol, KIM, Soo Youl, KANG, Suk Bum
Format Patent
LanguageEnglish
French
Korean
Published 28.05.2020
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Summary:The present invention relates to a pharmaceutical composition or an adjuvant anti-cancer agent for preventing or treating cancer comprising both streptonigrin and and one or more anti-cancer agents selected from the group consisting of cisplatin, gemcitabine, and paclitaxel. Additionally, the present invention relates to a method for preventing or treating cancer comprising the step for administering, to a patient, the pharmaceutical composition comprising both streptonigrin and one or more anti-cancer agents selected from the group consisting of cisplatin, gemcitabine, and paclitaxel. Therefore, the composition according to the present invention comprising both streptonigrin and other anti-cancer agents is highly effective in inhibiting cancer cell growth, especially the growth of ovarian cancer cells, and thus can be effectively used in a composition or method using the composition for preventing or treating cancer. La présente invention concerne une composition pharmaceutique ou un agent anticancéreux adjuvant pour la prévention ou le traitement du cancer comprenant à la fois la streptonigrine et un ou plusieurs agents anticancéreux choisis dans le groupe constitué de cisplatine, de gemcitabine et de paclitaxel. De plus, la présente invention concerne un procédé de prévention ou de traitement du cancer comprenant l'étape pour administrer, à un patient, la composition pharmaceutique comprenant à la fois de la streptonigrine et un ou plusieurs agents anticancéreux choisis dans le groupe constitué de cisplatine, de gemcitabine et de paclitaxel. Par conséquent, la composition selon la présente invention comprenant à la fois la streptonigrine et d'autres agents anticancéreux est hautement efficace dans l'inhibition de la croissance des cellules cancéreuses, en particulier la croissance de cellules cancéreuses ovariennes, et peut ainsi être efficacement utilisée dans une composition ou un procédé utilisant la composition pour prévenir ou traiter le cancer. 본 발명은 스트렙토니그린; 및 시스플라틴, 겜시타빈 및 파클리탁셀로 이루어진 군에서 선택되는 어느 하나 이상의 추가 항암제; 를 모두 포함하는 암 예방 또는 치료에 사용하기 위한 약학적 조성물 내지 항암보조제에 대한 것이다. 또한, 스트렙토니그린; 및 시스플라틴, 겜시타빈 및 파클리탁셀로 이루어진 군에서 선택되는 어느 하나 이상의 추가 항암제; 를 모두 포함하는 약학적 조성물을 환자에게 투여하는 단계를 포함하는 암 예방 또는 치료방법에 대한 것이다. 따라서, 본 발명의 스트렙토니그린과 다른 항암제들을 모두 포함하는 조성물은 암세포의 생장을 억제하는 효과, 특히 난소암 세포에 대하여 그 생장을 억제하는 효과가 우수하므로, 암 예방 또는 치료용 조성물 내지 이를 이용한 암 예방 또는 치료방법에 효과적으로 사용될 수 있다.
Bibliography:Application Number: WO2019KR15907