NOVEL ARYLALKYL PYRAZOLE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS

Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed...

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Main Authors GUO, Liangqin, CLAUSEN, Dane, LIM, Jongwon, HE, Shuwen, XIAO, Li, HAN, Yongxin, MARTINOT, Theodore, YU, Wensheng, FRADERA, Xavier, CHEN, Ping, PASTERNAK, Alexander
Format Patent
LanguageEnglish
French
Published 23.04.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder. L'invention concerne des composés de formule (I) qui sont des inhibiteurs d'une enzyme IDO, ainsi que des utilisations desdits composés dans le traitement potentiel ou la prévention potentielle d'une maladie ou d'un trouble associé à l'IDO. L'invention concerne également des compositions comprenant ces composés. L'invention concerne en outre des utilisations desdites compositions dans le traitement potentiel ou la prévention potentielle d'une maladie ou d'un trouble associé à l'IDO.
Bibliography:Application Number: WO2019US55761