GENETIC ENGNEERING OF B CELL RECEPTORS AND USES THEREOF IN ANTIGEN-INDUCED ANTIBODY SECRETION

The present invention relates to methods and compositions for engineering B cells to express transgenic B cell receptor (BCR) for antigen-induced antibody secretion, compositions, methods and uses thereof in immunotherapy. La présente invention concerne des procédés et des compositions pour la modif...

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Bibliographic Details
Main Authors NAHMAD, Alessio D, BARZEL, Adi, DOTAN, Iris, FRIED, Miriam, AKRIV, Tal, NATAF, Daniel
Format Patent
LanguageEnglish
French
Published 29.04.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to methods and compositions for engineering B cells to express transgenic B cell receptor (BCR) for antigen-induced antibody secretion, compositions, methods and uses thereof in immunotherapy. La présente invention concerne des procédés et des compositions pour la modification de lymphocytes B pour exprimer le récepteur des lymphocytes B transgéniques (BCR) pour la sécrétion d'anticorps induite par l'antigène, des compositions, des procédés et des utilisations de ceux-ci en immunothérapie.
Bibliography:Application Number: WO2019IL51026