IMIDAZOPYRAZINE INHIBITORS OF INTERLEUKIN-2-INDUCIBLE T-CELL KINASE
In some embodiments, the invention relates to an interleukin-2- inducible T-cell kinase (ITK) inhibitor of formula (I) or a pharmaceutically acceptable salt thereof, or to pharmaceutical compositions comprising these compounds and to their use in the treatment of ITK mediated disorders. Dans certain...
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Language | English French |
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19.12.2019
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Abstract | In some embodiments, the invention relates to an interleukin-2- inducible T-cell kinase (ITK) inhibitor of formula (I) or a pharmaceutically acceptable salt thereof, or to pharmaceutical compositions comprising these compounds and to their use in the treatment of ITK mediated disorders.
Dans certains modes de réalisation, l'invention concerne un inhibiteur de kinase de lymphocytes T inductible par l'interleukine-2 (kinase ITK) de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, ou des compositions pharmaceutiques comprenant ces composés et leur utilisation dans le traitement de troubles médiés par la kinase ITK. (I) |
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AbstractList | In some embodiments, the invention relates to an interleukin-2- inducible T-cell kinase (ITK) inhibitor of formula (I) or a pharmaceutically acceptable salt thereof, or to pharmaceutical compositions comprising these compounds and to their use in the treatment of ITK mediated disorders.
Dans certains modes de réalisation, l'invention concerne un inhibiteur de kinase de lymphocytes T inductible par l'interleukine-2 (kinase ITK) de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, ou des compositions pharmaceutiques comprenant ces composés et leur utilisation dans le traitement de troubles médiés par la kinase ITK. (I) |
Author | DEMONT, Dennis COVEY, Todd VERKAIK, Saskia DE ZWART, Edwin KAPTEIN, Allard HOOGENBOOM, Niels BARF, Tjeerd |
Author_xml | – fullname: DE ZWART, Edwin – fullname: VERKAIK, Saskia – fullname: HOOGENBOOM, Niels – fullname: BARF, Tjeerd – fullname: COVEY, Todd – fullname: DEMONT, Dennis – fullname: KAPTEIN, Allard |
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DocumentTitleAlternate | INHIBITEURS IMIDAZOPYRAZINES DE KINASE DE LYMPHOCYTES T INDUCTIBLE PAR L'INTERLEUKINE-2 |
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Snippet | In some embodiments, the invention relates to an interleukin-2- inducible T-cell kinase (ITK) inhibitor of formula (I) or a pharmaceutically acceptable salt... |
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Title | IMIDAZOPYRAZINE INHIBITORS OF INTERLEUKIN-2-INDUCIBLE T-CELL KINASE |
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