MODIFIED GUIDE RNAS FOR GENE EDITING

This disclosure relates to modified guide RNAs having improved in vitro and in vivo activity in gene editing methods. La présente invention concerne des ARN guides modifiés ayant une activité in vitro et in vivo améliorée dans des procédés d'édition de gènes.

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Bibliographic Details
Main Authors BROWN, Robert, LESCARBEAU, Reynald Michael, PARMAR, Rubina, SMITH, Amy Madison Rhoden, ROY, Matthew, SALERNO, Paige, BROWN, Duncan, LESCARBEAU, Rebecca, ALEXANDER, Seth, LANBA, Adhiraj, SEITZER, Jessica Lynn
Format Patent
LanguageEnglish
French
Published 12.12.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:This disclosure relates to modified guide RNAs having improved in vitro and in vivo activity in gene editing methods. La présente invention concerne des ARN guides modifiés ayant une activité in vitro et in vivo améliorée dans des procédés d'édition de gènes.
Bibliography:Application Number: WO2019US36160