PEGYLATED COMPOSITIONS FOR OCULAR USE, AND METHODS THEREOF

• Main Authors: ERICKSON, Carl, QUICK, Ryan, RUSCONI, Christopher P, MCARDLE, James V, LEVY, Matthew
• Format: Patent
• Language: English; French
• Published: 31.10.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

This disclosure provides PEGylated aptamers that contain PEG reagents with branching configurations useful for therapeutic applications, such as intraocular injection. This disclosure also provides methods for treating ocular disorders involving administering therapeutic PEGylated aptamers with bran...