PEGYLATED COMPOSITIONS FOR OCULAR USE, AND METHODS THEREOF

This disclosure provides PEGylated aptamers that contain PEG reagents with branching configurations useful for therapeutic applications, such as intraocular injection. This disclosure also provides methods for treating ocular disorders involving administering therapeutic PEGylated aptamers with bran...

Full description

Saved in:
Bibliographic Details
Main Authors ERICKSON, Carl, QUICK, Ryan, RUSCONI, Christopher P, MCARDLE, James V, LEVY, Matthew
Format Patent
LanguageEnglish
French
Published 31.10.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:This disclosure provides PEGylated aptamers that contain PEG reagents with branching configurations useful for therapeutic applications, such as intraocular injection. This disclosure also provides methods for treating ocular disorders involving administering therapeutic PEGylated aptamers with branching configurations to a subject with an ocular disorder. La présente invention concerne des aptamères PEGylés qui contiennent des réactifs PEG présentant des configurations de ramification utiles pour des applications thérapeutiques, telles qu'une injection intraoculaire. La présente invention concerne également des méthodes de traitement de troubles oculaires impliquant l'administration d'aptamères PEGylés thérapeutiques présentant des configurations de ramification à un sujet atteint d'un trouble oculaire.
Bibliography:Application Number: WO2019US29384