GROWTH DIFFERENTIATION FACTOR 15 AGONIST COMPOUNDS AND METHODS OF USING THE SAME

Compounds are provided herein that induce weight loss and that treat diabetes, dyslipidemia, NASH and/or obesity. Also provided are pharmaceutical compositions containing such compounds and therapeutic uses of such compounds and compositions, where such compounds act as GDF15 agonists with extended...

Full description

Saved in:
Bibliographic Details
Main Authors PICKARD, Richard Todd, GONCIARZ, Malgorzata Donata, OBUNGU, Victor H
Format Patent
LanguageEnglish
French
Published 10.10.2019
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online AccessGet full text

Cover

More Information
Summary:Compounds are provided herein that induce weight loss and that treat diabetes, dyslipidemia, NASH and/or obesity. Also provided are pharmaceutical compositions containing such compounds and therapeutic uses of such compounds and compositions, where such compounds act as GDF15 agonists with extended time of action and other advantageous properties. L'invention concerne des composés permettant d'induire une perte de poids, destinés au traitement du diabète, de la dyslipidémie, la NASH et/ou l'obésité. L'invention concerne également des compositions pharmaceutiques contenant de tels composés et des utilisations thérapeutiques de ces composés et compositions, les composés agissent en tant qu'agonistes de GDF15 avec un temps d'action prolongé ainsi que d'autres propriétés avantageuses.
Bibliography:Application Number: WO2019US24756