NOVEL COMBINATIONS OF A TUBULIN POLYMERIZATION INHIBITOR AND A POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITOR FOR USE IN THE TREATMENT OF CANCER

Methods and combination therapies for treating, preventing, and/or delaying the onset and/or development of cancer using a tubulin polymerization inhibitor such as a compound of formula I,or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose) polymerase (PARP) inhibitor,or a pharmace...

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Bibliographic Details
Main Authors REHNMARK, Stefan, HÖGBERG, Marita
Format Patent
LanguageEnglish
French
Published 10.10.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Methods and combination therapies for treating, preventing, and/or delaying the onset and/or development of cancer using a tubulin polymerization inhibitor such as a compound of formula I,or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose) polymerase (PARP) inhibitor,or a pharmaceutically acceptable salt thereof, are provided. L'invention concerne des méthodes et des polythérapies permettant de traiter, de prévenir et/ou de retarder l'apparition et/ou le développement d'un cancer en faisant appel à un inhibiteur de polymérisation de la tubuline tel qu'un composé de formule I, ou un sel pharmaceutiquement acceptable de celui-ci, et à un inhibiteur de la poly(ADP-ribose) polymérase (PARP), ou un sel pharmaceutiquement acceptable de celui-ci.
Bibliography:Application Number: WO2019SE50312