CRYSTALLINE FORMS OF MODULATORS OF CFTR

Crystalline Forms of Compound (I); crystalline Forms of Compound (II) and crystalline forms of pharmaceutically acceptable salts of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same...

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Main Authors LEE, Elaine Chungmin, NAVAMAL, Mettachit, ZWICKER, Carl, SHI, Yi, ZHANG, Beili, SHRESTHA, Muna, NTI-ADDAE, Kwame Wiredu
Format Patent
LanguageEnglish
French
Published 03.10.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Crystalline Forms of Compound (I); crystalline Forms of Compound (II) and crystalline forms of pharmaceutically acceptable salts of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. L'invention concerne des formes cristallines du composé (I), des formes cristallines du composé (II) et des formes cristallines de sels pharmaceutiquement acceptables de l'un quelconque de ceux-ci. L'invention concerne également des compositions pharmaceutiques les comprenant, des procédés de traitement de la fibrose kystique à l'aide de celles-ci, et leurs procédés de fabrication.
Bibliography:Application Number: WO2019US24890