INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE

Inhibitors of Glycerol 3-Phosphate Acyltransferase (GPAT) are provided; and methods of use in the treatment of cancer; and treatment of conditions relating to metabolic syndrome and hyperlipidemia. L'invention concerne des inhibiteurs de glycérol 3-phosphate acyltransférase (GPAT); et des procé...

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Main Authors JIN, Feng, ZARE, Richard N, FELSHER, Dean W, GOUW, Arvin, MARGULIS, Katherine, RICHARDS, Steven, SCHOW, Steven R, GREENHOUSE, Robert, LOUGHHEAD, David Garrett
Format Patent
LanguageEnglish
French
Published 29.08.2019
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Inhibitors of Glycerol 3-Phosphate Acyltransferase (GPAT) are provided; and methods of use in the treatment of cancer; and treatment of conditions relating to metabolic syndrome and hyperlipidemia. L'invention concerne des inhibiteurs de glycérol 3-phosphate acyltransférase (GPAT); et des procédés d'utilisation dans le traitement du cancer; et le traitement d'états associés au syndrome métabolique et à l'hyperlipidémie.
Bibliography:Application Number: WO2019US19185