PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES

The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as, but not confined to, SLE and geographic atrophy. L�...

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Main Authors RICHARDSON, Anthony John, TOWNSEND, Robert James, LI, Xianfu, LALLEMAND, Benedicte, LLAVERIA CROS, Josep, HALLSIDE, Michal Sarah, HEER, Jag Paul, SMALLEY, Adam Peter, LOWE, Martin Alexander
Format Patent
LanguageEnglish
French
Published 22.08.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as, but not confined to, SLE and geographic atrophy. L'invention concerne des dérivés cycliques 6,5 hétérobicycliques de formule (I), leurs procédés de préparation, des compositions pharmaceutiques les contenant et leur utilisation pour le traitement d'états inflammatoires entraînés par activation STING, tels que, mais pas confinés à, SLE et l'atrophie géographique.
Bibliography:Application Number: WO2019EP53893