METHODS OF CANCER TREATMENT USING AN ATR INHIBITOR

The present disclosure relates to methods of identifying a cancer having sensitivity to an ATR inhibitor compound, and treating subjects with such identified cancers with the ATR inhibitor, particularly in combination with a DNA damaging agent. La présente invention concerne des méthodes d'iden...

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Bibliographic Details
Main Authors PENNEY, Marina, SULLIVAN, James, REAPER, Philip Michael, GEHO, David, TAKEMOTO, Darin, POLLARD, John Robert
Format Patent
LanguageEnglish
French
Published 04.07.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The present disclosure relates to methods of identifying a cancer having sensitivity to an ATR inhibitor compound, and treating subjects with such identified cancers with the ATR inhibitor, particularly in combination with a DNA damaging agent. La présente invention concerne des méthodes d'identification d'un cancer présentant une sensibilité à un composé inhibiteur d'ATR, et de traitement de sujets atteints de tels cancers identifiés avec l'inhibiteur d'ATR, en particulier en association avec un agent endommageant l'ADN.
Bibliography:Application Number: WO2018US67673