METHODS AND COMPOSITIONS FOR THE TREATMENT OF WOUNDS

The methods and compositions described herein address the need in the art by providing peptides and polypeptides comprising a growth factor binding domain. In some embodiments, the peptides have an amino acid sequence that is at least 80% identical to one of SEQ ID NOS:1-7, 13-15, 49-50, or 66-70, o...

Full description

Saved in:
Bibliographic Details
Main Authors BRIQUEZ, Priscilla, STARKE, Richard, ISHIHARA, Jun, ISHIHARA, Ako, HUBBELL, Jeffrey A, RANDI, Anna M
Format Patent
LanguageEnglish
French
Published 16.05.2019
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online AccessGet full text

Cover

More Information
Summary:The methods and compositions described herein address the need in the art by providing peptides and polypeptides comprising a growth factor binding domain. In some embodiments, the peptides have an amino acid sequence that is at least 80% identical to one of SEQ ID NOS:1-7, 13-15, 49-50, or 66-70, or a fragment thereof; wherein the peptide is less than 300 amino acids in length. Les procédés et les compositions de l'invention résolvent un besoin de l'état de la technique en fournissant des peptides et des polypeptides comprenant un domaine de liaison à un facteur de croissance. Dans certains modes de réalisation, les peptides comportent une séquence d'acides aminés qui est identique à au moins 80 % à l'une des SEQ ID NO : 1-7, 13-15, 49-50 ou 66-70, ou à un fragment de celles-ci ; le peptide étant un peptide de moins de 300 acides aminés de long.
Bibliography:Application Number: WO2018US60760