PHARMACEUTICAL COMPOSITION CONTAINING AGOMELATINE AND PROCESS FOR THE PREPARATION THEREOF

The present invention relates to a pharmaceutical composition comprising agomelatine, in particular agomelatine in crystalline form, especially agomelatine in in polymorphic form X or I,and a pH modifier and optionally polymeric material, as well as to a process for the preparation thereof. La prése...

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Bibliographic Details
Main Authors PAVLIN, Darja, VRECER, Franc, MATEOVIC-ROJNIK, Tatjana, MEZNAR, Klavdija, VRBINC, Miha
Format Patent
LanguageEnglish
French
Published 18.04.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a pharmaceutical composition comprising agomelatine, in particular agomelatine in crystalline form, especially agomelatine in in polymorphic form X or I,and a pH modifier and optionally polymeric material, as well as to a process for the preparation thereof. La présente invention concerne une composition pharmaceutique comprenant de l'agomélatine, en particulier de l'agomélatine sous forme cristalline, en particulier de l'agomélatine sous forme polymorphe X ou I, et un modificateur de pH et facultativement un matériau polymère, ainsi qu'un procédé pour sa préparation.
Bibliography:Application Number: WO2018EP77507