ANTI-HUMAN α9 INTEGRIN ANTIBODY-CONTAINING PHARMACEUTICAL COMPOSITION

• Main Authors: MORISHIGE Tomohiro, KAWANO Hiroki
• Format: Patent
• Language: English; French; Japanese
• Published: 04.04.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Provided is a stable pharmaceutical composition containing an anti-human α9 integrin antibody that suppresses the production of multimers, degradation products, insoluble impurities, or insoluble microparticles. The pharmaceutical composition contains a pharmaceutically acceptable buffer, and the pH is 5.0-7.0. La présente invention concerne une composition pharmaceutique stable contenant un anticorps anti-intégrine α9 humaine qui supprime la production de multimères, de produits de dégradation, d'impuretés insolubles ou de microparticules insolubles. La composition pharmaceutique contient un tampon pharmaceutiquement acceptable, et le pH est de 5,0 à 7,0. 多量体、分解物、不溶性異物、又は不溶性微粒子の生成を抑制してなる、抗ヒトα９インテグリン抗体を含有してなる、安定な医薬組成物を提供する。前記医薬組成物は、製薬学的に許容される緩衝剤を含有してなり、ｐＨが５．０～７．０である。