ANTI-L1-CAM ANTIBODIES AND USES THEREOF

The present disclosure relates generally to immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that can bind to and neutralize the activity of L1-CAM protein. The antibodies of the present technology are useful in methods for detecting and treating a L1-CAM-p...

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Bibliographic Details
Main Authors SUZUKI-NISHIJIMA, Maya, CHEUNG, Nai-Kong, LEWIS, Jason, XU, Hong, NEMIEBOKA, Brandon
Format Patent
LanguageEnglish
French
Published 20.12.2018
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure relates generally to immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that can bind to and neutralize the activity of L1-CAM protein. The antibodies of the present technology are useful in methods for detecting and treating a L1-CAM-positive cancer in a subject in need thereof. De manière générale, la présente divulgation concerne des compositions associées à des immunoglobulines (p. ex., anticorps ou fragments de ceux-ci se liant à l'antigène) qui peuvent se lier à, et neutraliser l'activité de la protéine L1-CAM. Les anticorps selon la présente technologie sont utiles dans des méthodes de dépistage et de traitement d'un cancer positif à L1-CAM chez un sujet en ayant besoin.
Bibliography:Application Number: WO2018US37645