CD2-ASSOCIATED PROTEIN (CD2AP) AND ITS INTERACTIVE PROTEINS

• Main Authors: LI, Chaoyang, ZHANG, Huixia
• Format: Patent
• Language: English; French
• Published: 20.12.2018
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

A method for down-regulating CD2AP expression in a subject comprises administering a CD2AP down-regulation composition to the subject, wherein the CD2AP down regulation composition is workable by way of siRNA/shRNA, Crispr/cas9, crispr/cpf1, Talen or ZFNs; thereby the CD2AP expression in liver tissues of the subject is down-regulated. La présente invention concerne un procédé de régulation à la baisse de l'expression de CD2AP chez un sujet qui consiste à administrer au sujet une composition de régulation à la baisse de CD2AP, la composition de régulation à la baisse de CD2AP étant utilisable au moyen d'ARNsi/shARN, de CRISPR/cas9, de CRISPR/cpf1, de Talen ou de NDZ ; ainsi, l'expression de CD2AP dans les tissus du foie du sujet est régulée à la baisse.