IMPROVED PROCESS FOR PREPARATION OF FOSAPREPITANT OR SALT THEREOF

The present invention relates to an improved process for the preparation of fosaprepitant or salt thereof. More particularly, the present invention relates to an effective process for the preparation of fosaprepitant dibenzylester, a compound of Formula II, which is a useful intermediate in the prep...

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Bibliographic Details
Main Authors NAIK, Samir, TEWARI, Amit, JAGADALE, Shivaji Eknath, BHIRUD, Shekhar Bhaskar, CHORAGHE, Mahendra Joma, KAJALE, Yogesh Baburao
Format Patent
LanguageEnglish
French
Published 22.11.2018
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to an improved process for the preparation of fosaprepitant or salt thereof. More particularly, the present invention relates to an effective process for the preparation of fosaprepitant dibenzylester, a compound of Formula II, which is a useful intermediate in the preparation of fosaprepitant or fosaprepitant dimeglumine. L'invention concerne un procédé amélioré de préparation de fosaprépitant ou d'un sel de celui-ci. L'invention concerne plus particulièrement un procédé efficace de préparation de dibenzylester de fosaprépitant, un composé de formule II, qui est un intermédiaire utile dans la préparation de fosaprépitant ou de fosaprépitant diméglumine.
Bibliography:Application Number: WO2018IB53367