METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE

A method of modulating ribonucleotide reductase activity in a neoplastic cell includes administering to the cell an amount of a triazole or an oxadiazole ribonucleotide reductase modulator (RRmod), the amount being effective to inhibit neoplastic cell growth. L'invention concerne un procédé de...

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Bibliographic Details
Main Authors VISWANATHAN, Rajesh, HUFF, Sarah E, HARTE, William, DEALWIS, Chris G
Format Patent
LanguageEnglish
French
Published 11.10.2018
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A method of modulating ribonucleotide reductase activity in a neoplastic cell includes administering to the cell an amount of a triazole or an oxadiazole ribonucleotide reductase modulator (RRmod), the amount being effective to inhibit neoplastic cell growth. L'invention concerne un procédé de modulation de l'activité ribonucléotide réductase dans une cellule néoplasique qui comprend l'administration à la cellule d'une quantité d'un modulateur de ribonucléotide réductase (RRmod) triazole ou oxadiazole, la quantité étant efficace pour inhiber la croissance des cellules néoplasiques.
Bibliography:Application Number: WO2018US26098