UNYLINKER RAPID CLEAVAGE
The present invention relates to the field of oligonucleotide synthesis using a solid support and in particular to the finding the when using a 3' oxy-LNA nucleoside attached to the solid support of the UnyLinker types, cleavage and deprotection occurs very rapidly. La présente invention concer...
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Main Authors | , , |
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Format | Patent |
Language | English French |
Published |
04.10.2018
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to the field of oligonucleotide synthesis using a solid support and in particular to the finding the when using a 3' oxy-LNA nucleoside attached to the solid support of the UnyLinker types, cleavage and deprotection occurs very rapidly.
La présente invention concerne le domaine de la synthèse d'oligonucléotides à l'aide d'un support solide et, concerne particulièrement, la découverte que le clivage et la déprotection se produisent très rapidement, lors de l'utilisation d'un nucléoside 3'oxy-LNA fixé au support solide des lieurs de type UnyLinker. |
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Bibliography: | Application Number: WO2018EP57296 |