AMPLIFICATION-INTEGRATED GENETIC MATERIAL DEPLETION OF NON-TARGET ORGANISMS USING DIFFERENTIALLY ABUNDANT K-MERS

The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers (3) are applied that show a difference in frequency and/or context in the genome (2) of the at least one microorg...

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Bibliographic Details
Main Authors MATZAS, Mark, POSCH, Andreas Emanuel, HUANG, Yiwei, DIETRICH, Carsten
Format Patent
LanguageEnglish
French
Published 28.06.2018
Subjects
BEER
BIOCHEMISTRY
CALCULATING
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPUTING
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers (3) are applied that show a difference in frequency and/or context in the genome (2) of the at least one microorganism and/or virus compared to the genome of the subject (1). La présente invention concerne un procédé d'amplification sélective d'au moins une séquence d'acide nucléique d'au moins un micro-organisme et/ou virus dans un échantillon d'un sujet, des k-mères (3) étant appliqués qui présentent une différence de fréquence et/ou de contexte dans le génome (2) dudit au moins un micro-organisme et/ou virus par rapport au génome du sujet (1).
Bibliography:Application Number: WO2017EP80666