STABLE PHARMACEUTICAL COMPOSITION COMPRISING CARBETOCIN AND SUITABLE FOR VAGINAL ADMINISTRATION, AND PREPARATION METHOD THEREFOR

A pharmaceutical composition comprising carbetocin, comprising (percent by weight): 0.5%-7% of carbetocin, 1%-10% of a water-soluble matrix material, 0.5%-5% of an amino acid anionic surfactant, 0.1%-5% of a humectant, and the balance of water. The amino acid anionic surfactant in the pharmaceutical...

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Bibliographic Details
Main Authors LIN, Hao Wen, TAO, An Jin, LING, Ru Guang, YUAN, Jian Cheng, ZHENG, Chun Lian
Format Patent
LanguageChinese
English
French
Published 28.06.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A pharmaceutical composition comprising carbetocin, comprising (percent by weight): 0.5%-7% of carbetocin, 1%-10% of a water-soluble matrix material, 0.5%-5% of an amino acid anionic surfactant, 0.1%-5% of a humectant, and the balance of water. The amino acid anionic surfactant in the pharmaceutical composition can effectively eliminate the clinical difference caused by the individual difference, can effectively and stably stimulate uterine contraction, and can maintain the stability of a drug. L'invention concerne une composition pharmaceutique comprenant de la carbétocine, comprenant (pour cent en poids) : 0,5 % à 7 % de carbétocine, 1 % à 10 % d'un matériau de matrice soluble dans l'eau, 0,5 % à 5 % d'un tensioactif anionique d'acide aminé, 0,1 % à 5 % d'un humectant, et le reste d'eau. Le tensioactif anionique d'acide aminé dans la composition pharmaceutique peut éliminer efficacement la différence clinique provoquée par la différence individuelle, peut stimuler efficacement et de manière stable la contra
Bibliography:Application Number: WO2017CN92718