ASSESSMENT OF STABILITY OF BIOLOGICAL PRODUCT IN PREFILLED SYRINGES

The invention relates to a method to mimic and assess the chemical degradation risk of a biological product, in prefilled syringes (PFS), using a custom-designed mimetic peptide. Such method is also able to predict the susceptibility to degradation of biological product in solution in a container fo...

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Bibliographic Details
Main Authors HAMEL, Jean-Bernard, BRUNET, Claire
Format Patent
LanguageEnglish
French
Published 24.05.2018
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The invention relates to a method to mimic and assess the chemical degradation risk of a biological product, in prefilled syringes (PFS), using a custom-designed mimetic peptide. Such method is also able to predict the susceptibility to degradation of biological product in solution in a container for medical usage. L'invention concerne un procédé permettant de reproduire et d'évaluer le risque de dégradation chimique d'un produit biologique dans des seringues pré-remplies au moyen d'un peptide mimétique conçu sur mesure. Le procédé selon l'invention permet également de prédire la sensibilité à la dégradation d'un produit biologique en solution dans un contenant à usage médical.
Bibliography:Application Number: WO2017EP78452