METHOD FOR PRODUCING PELLETS FOR CONTROLLED DELIVERY OF AN ACTIVE
A process for preparing granules for delayed release of an active comprising: extruding a tube of biodegradable polymer; inserting within the tube a plurality of longitudinally spaced portions of a core matrix comprising the active; and sealing the tube between the longitudinally spaced portions to...
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Main Authors | , , , |
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Format | Patent |
Language | English French |
Published |
05.04.2018
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Subjects | |
Online Access | Get full text |
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Summary: | A process for preparing granules for delayed release of an active comprising: extruding a tube of biodegradable polymer; inserting within the tube a plurality of longitudinally spaced portions of a core matrix comprising the active; and sealing the tube between the longitudinally spaced portions to form discrete granules comprising portions of core matrix.
La présente invention concerne un procédé de préparation de granulés destinés à la libération retardée d'un principe actif, lequel procédé consiste : à extruder un tube de polymère biodégradable ; à insérer à l'intérieur du tube une pluralité de parties espacées longitudinalement d'une matrice centrale comprenant le principe actif; et à sceller le tube entre les parties espacées longitudinalement afin de former des granulés discrets comprenant des parties de matrice centrale. |
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Bibliography: | Application Number: WO2017AU51067 |