ACID ADDITION SALT OF BENZIMIDAZOLE DERIVATIVE
The present invention relates to pidolate and malate salts of a compound represented by chemical formula 1 and preparation methods therefor, wherein the compound has preventive and therapeutic uses for a disease mediated by acid pump antagonistic activity and is excellent in liquid-phase stability,...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French Korean |
Published |
29.03.2018
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to pidolate and malate salts of a compound represented by chemical formula 1 and preparation methods therefor, wherein the compound has preventive and therapeutic uses for a disease mediated by acid pump antagonistic activity and is excellent in liquid-phase stability, solid-phase stability, solubility in water, precipitation stability, and hygroscopicity.
La présente invention concerne des sels de pidolate et de malate d'un composé représenté par la formule chimique 1 et leurs procédés de préparation, le composé ayant des utilisations préventives et thérapeutiques pour une maladie médiée par l'activité antagoniste de la pompe à acide et présentant une excellente stabilité en phase liquide, en phase solide, dans l'eau, en précipitation et une hygroscopicité.
본 발명은 산 펌프 길항 활성에 의해 매개되는 질환의 예방 및 치료용도를 갖는 화합물로서 액상 안정성과 고체상 안정성, 수용해도, 석출 안정성, 흡습성이 모두 우수한 화학식 1로 표시되는 화합물의 피돌레이트 염 및 말레이트 염, 및 이들의 제조방법에 관한 것이다. |
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Bibliography: | Application Number: WO2017KR10332 |