UPPER GASTROINTESTINAL FLORA-IMPROVING AGENT

• Main Authors: KOGA, Yasuhiro, NAKAE, Hirohiko, OHTSU, Toshihiro
• Format: Patent
• Language: English; French; Japanese
• Published: 28.12.2017
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The problem is solved by an upper gastrointestinal flora-improving agent, the agent containing lactobacilli as an active ingredient, to be used in persons positive and negative for Helicobacter pylori. Lactobacilli of the genus Lactobacillus are preferably used as the lactobacilli, more preferably Lactobacillus gasseri OLL 2716 (FERM BP-6999). Improvement of the upper gastrointestinal flora is, for example, a reduction in upper gastrointestinal bifidobacteria and/or an increase in upper gastrointestinal Prevotella bacteria. L'invention concerne un agent prophylactique et/ou thérapeutique pour troubles gastro-intestinaux fonctionnels. L'agent contient des lactobacilles, en tant qu'ingrédient actif, à utiliser chez des individus positifs et négatifs pour Helicobacter pylori. Les lactobacilles utilisés sont de préférence les lactobacilles du genre Lactobacillus, préférablement du Lactobacillus gasseri OLL 2716 (FERM BP -6999). L'amélioration de la flore gastro-intestinale supérieure est une réduction des bifidobactéries gastro-intestinales supérieures et/ou une augmentation des bactéries prévotella gastro-intestinales supérieures. ヘリコバクター・ピロリの陽性者及び陰性者用であり、乳酸菌を有効成分として含有する上部消化管内菌叢改善剤により、課題は解決される。乳酸菌としては、ラクトバチルス属乳酸菌を用いることが好ましく、ラクトバチルス・ガセリ（Lactobacillus　gasseri）　ＯＬＬ　２７１６（ＦＥＲＭ　ＢＰ－６９９９）を用いることがより好ましい。上部消化管内菌叢改善は、例えば、上部消化管内ビフィズス菌低減及び／又は上部消化管内プレボテラ菌増加である。