PROCESS FOR PREPARATION OF SACUBUTRIL INTERMEDIATE

The present application relates to a process for preparation of tert-butyl (R)-(1-([1,1'-biphenyl]-4- yl)-3-hydroxypropan-2-yl)carbamate (IA). The compound of formula (IA) may be used as an intermediate for the preparation of sacubitril. La présente invention concerne un procédé de préparation...

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Main Authors VARANASI, Ganesh, AALLA, Sampath, MAMIDIPALLI, Phani, KURELLA, Sreenivasulu, ADLA, Vijay, DAHANUKAR, Vilas Hareshwar, ELATI, Raviram Chandrasekhar
Format Patent
LanguageEnglish
French
Published 30.11.2017
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Summary:The present application relates to a process for preparation of tert-butyl (R)-(1-([1,1'-biphenyl]-4- yl)-3-hydroxypropan-2-yl)carbamate (IA). The compound of formula (IA) may be used as an intermediate for the preparation of sacubitril. La présente invention concerne un procédé de préparation de tert-butyl (R)-(1-([1,1'-biphényl]-4-yl)-3-hydroxypropan-2-yl) carbamate (IA). Le composé de formule (IA) peut être utilisé en tant qu'intermédiaire pour la préparation de sacubitril. (I)
Bibliography:Application Number: WO2017IB53105