HYDROXYALKYL-SUBSTITUTED HETEROARYLTRIAZOLE DERIVATIVES AND USES THEREOF

• Main Authors: NEUBAUER, Thomas, SCHMECK, Carsten, POOK, Elisabeth, COLLIN, Marie-Pierre, TINEL, Hanna, KOLKHOF, Peter, WITTWER, Matthias, Beat, WASNAIRE, Pierre, FÜRSTNER, Chantal, SCHIRMER, Heiko
• Format: Patent
• Language: English; French
• Published: 09.11.2017
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to novel 5-(hydroxyalkyl)-1-heteroaryl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases. La présente invention concerne de nouveaux dérivés de 5-(hydroxyalkyl)-1-hétéroaryl-1,2,4-triazole, des procédés de préparation de ces composés, des compositions pharmaceutiques contenant ces composés, et l'utilisation de ces composés ou compositions pour le traitement et/ou la prévention de maladies, en particulier pour le traitement et/ou la prévention de maladies cardiovasculaires et rénales.