RARA AGONISTS FOR THE TREATMENT OF AML AND MDS

Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations. La présente invention concerne des proc...

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Bibliographic Details
Main Authors FIORE, Christopher, FRITZ, Christian, EATON, Matthew Lucas, LEE, Emily Payton, MCKEOWN, Michael Robert
Format Patent
LanguageEnglish
French
Published 12.10.2017
Subjects
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations. La présente invention concerne des procédés qui définissent des populations cellulaires sensibles aux agonistes RARA et identifient des populations de patients qui bénéficieront d'un traitement avec des agonistes RARA. Les procédés peuvent comprendre l'administration d'agonistes RARA à des populations de patients.
Bibliography:Application Number: WO2017US26657