COMPOSITIONS AND METHODS FOR PREPARATION OF COMPOSITE POLYMER COATINGS ON MEDICAL IMPLANTS, AND THEIR USE FOR CO-DELIVERY OF MULTIPLE ANTIMICROBIAL AGENTS

• Main Authors: ZHENG, Jesse, ASHBAUGH, Alyssa, MILLER, Lloyd S, MAO, Hai-Quan, JIANG, Xuesong
• Format: Patent
• Language: English; French
• Published: 17.08.2017
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

The presently disclosed subject matter provides a coating composition which allows for the co-delivery of two or more bioactive agents with independent control of loading level and release profile for each bioactive agent, an implantable medical device coated with the coating composition, and methods for preparing the coating composition. La présente invention concerne une composition de revêtement qui permet l'administration conjointe d'au moins deux agents bioactifs avec le contrôle indépendant de niveau de chargement et de profil de libération pour chaque agent bioactif, un dispositif médical implantable revêtu de la composition de revêtement, et des procédés pour préparer la composition de revêtement.