THREE-DIMENSIONAL FIBROBLAST AGGREGATE AND IN VITRO 3D SKIN DERMIS MODEL COMPRISING SAME

• Main Authors: KIM, Sang Heon, PARK, Kwi Deok, CHOI, Jong Hoon
• Format: Patent
• Language: English; French; Korean
• Published: 18.05.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

Provided are: a three-dimensional fibroblast aggregate; a manufacturing method therefor; an in vitro three-dimensional skin dermis model comprising a fibroblast aggregate cultured from fibroblasts; and a method for screening a drug using the same. L'invention concerne : un agrégat tridimensionnel de fibroblastes; son procédé de fabrication; un modèle tridimensionnel de derme cutané in vitro comprenant un agrégat de fibroblastes cultivé à partir de fibroblastes; et un procédé de criblage d'un médicament l'utilisant. 3차원 섬유아세포집합체, 그의 제조방법, 및 섬유아세포로부터 배양된 섬유아세포집합체를 포함하는 인 비트로(In vitro) 3차원 피부 진피 모델 및 그를 사용하여 약물을 스크리닝하는 방법을 제공한다.