CYSTEINE PROTEASE INHIBITORS

The invention provides compounds and compositions that inhibit one or more cysteine proteases (e.g. caspases or cysteine cathepsins), as well as kits comprising such compounds and compositions. The invention also provides therapeutic methods and screening methods that utilize such compounds and comp...

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Bibliographic Details
Main Authors PHELPS, David, BARTIK, Mary, Margaret, HALVERSON, David, J, JOHNSON, Gary, BENSEN, Eric, S, BOGYO, Matthew, S
Format Patent
LanguageEnglish
French
Published 30.03.2017
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention provides compounds and compositions that inhibit one or more cysteine proteases (e.g. caspases or cysteine cathepsins), as well as kits comprising such compounds and compositions. The invention also provides therapeutic methods and screening methods that utilize such compounds and compositions. L'invention concerne des composés et des compositions qui inhibent une ou plusieurs protéases à cystéine (par exemple des caspases, ou des cathepsines à cystéine, ainsi que des kits comprenant de tels composés et de telles compositions. L'invention concerne également des méthodes thérapeutiques et des procédés de criblage qui utilisent de tels composés et de telles compositions.
Bibliography:Application Number: WO2016US53539