SOLID FORMS OF VALSARTAN AND SACUBITRIL

• Main Authors: PUTAPATRI, Siddamal Reddy, KHAIRNAR, Bhushan B, PANDEY, Gyanendra, SINGH, Kaptan, PRASAD, Mohan
• Format: Patent
• Language: English; French
• Published: 16.03.2017
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides solid forms comprising valsartan and sacubitril. The present invention provides solid salt forms comprising valsartan and sacubitril. The present invention further provides an amorphous solid salt form comprising sacubitril and valsartan. The present invention further provides processes for the preparation of the solid forms as described herein. The present invention further provides pharmaceutical compositions and a method of treatment of medical conditions responsive to the solid forms as described herein. La présente invention concerne des formes solides comprenant du valsartan et du sacubitril. La présente invention concerne des formes salines solides comportant du valsartan et du sacubitril. La présente invention concerne en outre une forme saline solide amorphe comportant du sacubitril et du valsartan. La présente invention concerne en outre des procédésde préparation des formes solides de l'invention. La présente invention concerne de plus des compositions pharmaceutiques et une méthode de traitement d'états pathologiques susceptible de répondre aux formes solides de l'invention.