SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS

• Main Authors: KAMBOJ, Rajender, Kumar, PATIL, Pradeep, Rangrao, WALKE, Deepak, Sahebrao, DAS, Amit, Kumar, KHAN, Talha, Hussain, DATRANGE, Laxmikant, Shamlal, PALLE, Venkata, P, RAMDAS, Vidya, JOSHI, Advait, Arun, KALHAPURE, Vaibhav, Madhukar, LORIYA, Rajeshkumar, Maganlal, BANERJEE, Moloy, GOTE, Ganesh, Navinchandra
• Format: Patent
• Language: English; French
• Published: 09.03.2017
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to sulfonamide compounds Formula (I) wherein the substituents are as described herein, and their use in a medicine for the treatment of diseases, disorders associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. It further relates to...