TRICYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER

There is provided compounds of formula (I), or pharmaceutically-acceptable salts thereof, wherein X, Y, Z, R1 and R2 have meanings provided in the description, which compounds are useful in the treatment of cancers. L'invention concerne des composés de formule (I) ou des sels pharmaceutiquement...

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Main Authors SIMEONOV, Anton, DEXHEIMER, Thomas, S, COUSSENS, Nathan, Patrick, MALONEY, David, Joseph, LUCI, Diane, Karen, STAFFORD, William, Chester, ARNER, Elias, Set Jenö, JADHAV, Ajit
Format Patent
LanguageEnglish
Published 20.04.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is provided compounds of formula (I), or pharmaceutically-acceptable salts thereof, wherein X, Y, Z, R1 and R2 have meanings provided in the description, which compounds are useful in the treatment of cancers. L'invention concerne des composés de formule (I) ou des sels pharmaceutiquement acceptables de ceux-ci. Dans la formule (I), X, Y, Z, R1 et R2 sont tels que décrits dans la description, lesquels composés sont utiles dans le traitement de cancers.
Bibliography:Application Number: WO2016US45730