SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY

The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other mic...

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Bibliographic Details
Main Authors HUANG, Haihong, ZHANG, Doongfeng, COOPER, Christopher, B, FOTOUHI, Nader, KANEKO, Takushi
Format Patent
LanguageEnglish
French
Published 26.01.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel oxazolidinones (Formula I): or a pharmaceutically acceptable salt having ring A characterized by N-containing monocyclic, bicyclic or spirocyclic substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments. La présente invention concerne de nouvelles oxazolidinones (Formule I) ou un sel pharmaceutiquement acceptable présentant le cycle A caractérisé par des substituants monocycles, bicycles ou spirocycles contenant N-, leur préparation, et leur utilisation en tant que médicaments pour traiter Mycobacterium tuberculosis et d'autres infections microbiennes, seules ou combinées à d'autres traitements anti-infectieux.
Bibliography:Application Number: WO2016US42486