CYTOTOXIC SUBSTITUTED 2-(1 H-PYRAZOL-1 -YL)-1,3-BENZOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF CANCER
The present invention relates to substituted 2-(1lH-pyrazol-1-yl)-1,3-benzothiazole compounds of general formula (I) : in which R1, R2, R3, R4, R5, R6 and R7 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutica...
Saved in:
Main Authors | , , , , , , , , , |
---|---|
Format | Patent |
Language | English French |
Published |
22.12.2016
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The present invention relates to substituted 2-(1lH-pyrazol-1-yl)-1,3-benzothiazole compounds of general formula (I) : in which R1, R2, R3, R4, R5, R6 and R7 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
La présente invention concerne des composés 2-(1H-pyrazol-1-yl)-1,3-benzothiazole substitués de formule générale (I) : dans laquelle R1, R2, R3, R4, R5, R6 et R7 sont tels que définis dans la description, des procédés de préparation desdits composés, des composés intermédiaires utiles pour préparer lesdits composés, des compositions et associations pharmaceutiques comprenant lesdits composés ainsi que l'utilisation desdits composés pour fabriquer une composition pharmaceutique destinée au traitement ou à la prophylaxie d'une maladie, en particulier des néoplasmes, comme agent seul ou en association avec d'autres principes actifs. |
---|---|
Bibliography: | Application Number: WO2016EP63546 |