METHOD FOR MANUFACTURING COLLAGEN FILM USING ULTRAVIOLET LIGHT, COLLAGEN FILM MANUFACTURED BY USING SAME, AND BIOMATERIAL PREPARED USING COLLAGEN FILM

• Main Authors: LEE, Myoung Sung, KIM, Ki Soo, CHANG, Cheong Ho, YOO, Ji Chul, LEE, Jun Keun, SUH, Dong Sam, LEE, Joon Ho
• Format: Patent
• Language: English; French; Korean
• Published: 08.12.2016
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; WORKING-UP

The present invention relates to a method for manufacturing a collagen film using ultraviolet light, the method comprising: a collagen solution preparing step for dissolving collagen in an acidic solution to prepare a collagen solution; a cross-linking step for irradiating ultraviolet light onto the collagen solution to physically cross-link the collagen solution; and a drying step for naturally drying the cross-linked collagen, to a collagen film manufactured by using the method for manufacturing a collagen film using ultraviolet light, and to a biomaterial prepared using the collagen film, such as a wound dressing, an artificial eardrum patch, a dental shielding film, an artificial cornea, an artificial lens, an anti-adhesion membrane, a drug delivery preparation, and an artificial organ. La présente invention concerne un procédé de fabrication d'un film de collagène à l'aide de lumière ultraviolette, le procédé comprenant : une étape de préparation de solution de collagène pour dissoudre le collagène dans une solution acide pour préparer une solution de collagène; une étape de réticulation pour exposer la solution de collagène à la lumière ultraviolette afin de réticuler physiquement la solution de collagène; et une étape de séchage pour sécher naturellement le collagène réticulé, un film de collagène fabriqué par le procédé de fabrication d'un film de collagène à l'aide de la lumière ultraviolette, et un matériau biologique préparé à l'aide du film de collagène, tel qu'un pansement, un timbre de tympan artificiel, un film de protection dentaire, une cornée artificielle, une lentille artificielle, une membrane anti-adhérence, une préparation d'administration de médicament, et un organe artificiel. 본 발명은 콜라겐을 산성 용액에 용해하여 콜라겐 용액을 제조하는 콜라겐 용액 제조단계; 상기 콜라겐 용액에 자외선을 조사하여 물리적으로 가교하는 가교단계; 및 상기 가교된 콜라겐을 자연 건조하는 건조단계;를 포함하는 자외선을 이용한 콜라겐 필름의 제조방법, 상기 자외선을 이용한 콜라겐 필름의 제조방법을 이용하여 제조된 콜라겐 필름 및 상기 콜라겐 필름을 이용하여 제조된 창상피복재, 인공 고막 패치, 치과용 차폐막, 인공 각막, 인공 렌즈, 유착방지막, 약물전달제재 및 인공장기 등과 같은 생체재료에 관한 것이다.