COMPOSITION CONTAINING CATIONIC HYDROXYETHYL CELLULOSE

• Main Authors: DIELMAN, Demetrius, JORDAN, Susan L, PARTAIN, Emmett M, CURTIS-FISK, Jaime L, KATZ, Joshua S, DEPUIT, Ryan J, TAN, Yujing
• Format: Patent
• Language: English; French
• Published: 06.10.2016
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR PREPARATION OR CHEMICAL WORKING-UP

An aqueous solution comprising a cationic polymer dissolved in water, wherein said cationic polymer comprises a hydrophobic quaternary ammonium group covalently attached to a hydroxyethyl cellulose polymer backbone. Also, a method of delivering a drug to a mucosal surface in a living body, said method comprising applying the aqueous solution to said mucosal surface. L'invention concerne une solution aqueuse comprenant un polymère cationique dissous dans de l'eau, ledit polymère cationique comprenant un groupe ammonium quaternaire hydrophobe lié de manière covalente à un squelette polymère à base d'hydroxyéthylcellulose. L'invention concerne également un procédé d'administration d'un médicament en direction d'une surface muqueuse chez un organisme vivant, ledit procédé comprenant l'application de la solution aqueuse sur ladite surface muqueuse.