PARTICLES OF N-(5-CYANO-4-((2-METHOXYETHYL)AMINO)PYRIDIN-2-YL)-7-FORMYL-6-((4-METHYL-2- OXOPIPERAZIN-1-YL)METHYL)-3,4-DIHYDRO-1,8-NAPHTHYRIDINE-1(2H)-CARBOXAMIDE

The present invention relates to particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7- formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, to a process of making said particles, to pharmaceutical compositions comprising said particles and to m...

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Bibliographic Details
Main Authors FURET, Pascal, KNOEPFEL, Thomas, MALLET, Franck, XIONG, Jing, WANG, Can, FAIRHURST, Robin Alec, HAN, Bo, ZHAO, Xianglin, MAH, Robert, LIAO, Lv, BUSCHMANN, Nicole, LEBLANC, Catherine, MARTZ, Julie
Format Patent
LanguageEnglish
French
Published 29.09.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7- formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, to a process of making said particles, to pharmaceutical compositions comprising said particles and to method of treating cancers using said pharmaceutical compositions. Cette invention concerne des particules de N-(5-cyano-4-((2-méthoxyéthyl)amino)pyridin-2-yl)-7-formyl-6-((4-méthyl-2-oxopipérazin-1-yl)méthyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, un procédé de fabrication desdites particules, des compositions pharmaceutiques les contenant et une méthode destinée à traiter les cancers à l'aide desdites compositions pharmaceutiques.
Bibliography:Application Number: WO2016IB51633