COMPOSITION COMPRISING ANAEROBICALLY CULTIVATED HUMAN INTESTINAL MICROBIOTA

• Main Authors: LÁZARO MALLÉN, Elisabet, CUÑÉ CASTELLANA, Jordi, SANTAS GUTIÉRREZ, Jonatan
• Format: Patent
• Language: English; French
• Published: 09.09.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

A method for preparing a composition comprising anaerobic human intestinal microbiota, wherein the method comprises the step of anaerobic cultivation of a fecal sample from a healthy donor in a cultivation medium, wherein the cultivation is done as a continuous cultivation process and the cultivation medium comprises dietary fibers. The obtained composition may e.g. be used for the treatment of Clostridium difficile infection. L'invention concerne un procédé de préparation d'une composition comprenant un microbiote intestinal humain anaérobie, le procédé comprenant l'étape de culture anaérobie d'un échantillon fécal provenant d'un donneur sain dans un milieu de culture, la culture étant effectuée sous la forme d'un procédé de culture continu et le milieu de culture comprenant des fibres alimentaires. La composition obtenue peut, par exemple, être utilisée pour le traitement d'une infection à Clostridium difficile.