NOVEL BINDING PROTEINS COMPRISING A UBIQUITIN MUTEIN AND ANTIBODIES OR ANTIBODY FRAGMENTS

The present invention relates novel binding molecules comprising a ubiquitin mutein (Affilin® ) and a monoclonal antibody or antibody fragment. The invention refers to bispecific and/or bivalent binding proteins or to a therapeutically or diagnostically active component. The invention further relate...

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Main Authors LIEBSCHER, MARKUS, BOSSE-DOENECKE, EVA, FIEDLER, ERIK, KAHL, MATHIAS, HENNICKE, JULIA, KNICK, PAUL, SETTELE, FLORIAN
Format Patent
LanguageEnglish
French
Published 11.08.2016
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates novel binding molecules comprising a ubiquitin mutein (Affilin® ) and a monoclonal antibody or antibody fragment. The invention refers to bispecific and/or bivalent binding proteins or to a therapeutically or diagnostically active component. The invention further relates to the use of these binding proteins ' medicine, preferably for use in the treatment of cancer or autoimmune disorders. L'invention concerne de nouvelles molécules de liaison comprenant une ubiquitine-mutéine (Affiline®) et un anticorps monoclonal ou fragment d'anticorps. L'invention concerne des protéines de liaison bispécifiques et/ou bivalentes ou un composant thérapeutiquement ou diagnostiquement actif. L'utilisation de ces protéines de liaison en médecine, de préférence pour traiter le cancer ou des troubles auto-immuns est en outre décrite.
Bibliography:Application Number: WO2016EP52345