DOSAGE REGIMEN FOR MADCAM ANTAGONISTS

The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided. La pré...

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Main Authors PRADHAN, VIVEKANANDA, CLARE, ROBERT A, TILLEY, MERA KRISHNAN, PAGE, KAREN MICHELLE, ZHANG, WEIDONG, CATALDI, FABIO, VON SCHACK, DAVID J, BANERJEE, ANINDITA, COMER, GAIL M, HASSAN-ZAHRAEE, MINA, VINCENT, MICHAEL STEVEN, AHMAD, ALAA
Format Patent
LanguageEnglish
French
Published 14.07.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided. La présente invention concerne une méthode pour le traitement d'un patient comprenant l'administration au patient d'une dose initiale comprise entre environ 1 mg et environ 150 mg d'un anticorps antagoniste de MAdCAM. L'invention concerne également des biomarqueurs pour évaluer la réponse d'un patient au traitement anti-MAdCAM.
Bibliography:Application Number: WO2016IB50047