PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF

Disclosed are a pyrrole amide compound as represented in formula I, polymorphs thereof, or pharmaceutically acceptable salts, hydrates, or solvate compounds. The present invention has good deacetylase inhibitory activity. Additionally, the preparation method for the compound involves few steps and i...

Full description

Saved in:
Bibliographic Details
Main Authors LI, XUEMING, WAN, JINQIAO, MU, YUN, LIU, SHAOJUN, LI, CAIKUI, LV, PENG, PAN, FEI, ZHONG, GUOQING, HU, XIAO, LI, JIN, GAO, JIAN, DOU, DENGFENG
Format Patent
LanguageChinese
English
French
Published 07.07.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Disclosed are a pyrrole amide compound as represented in formula I, polymorphs thereof, or pharmaceutically acceptable salts, hydrates, or solvate compounds. The present invention has good deacetylase inhibitory activity. Additionally, the preparation method for the compound involves few steps and is easy to operate, safe, and environmentally friendly, produces high yields, and is suitable for industrial application. L'invention concerne un composé pyrrole-amide tel que représenté par la formule I, des polymorphes de ce dernier, ou des sels pharmaceutiquement acceptables, hydrates, ou composés solvatés. La présente invention présente une bonne activité inhibitrice de la désacétylase. De plus, le procédé de préparation du composé implique peu d'étapes et est facile à utiliser. Ce dernier est sûr et respectueux de l'environnement, permet d'obtenir des rendements élevés, et est approprié à une application industrielle. 公开了一种式Ⅰ所示的吡咯酰胺类化合物或其晶型、药学上可接受的盐、水合物或溶剂合物。其具有良好的去乙酰化酶抑制活性；同时，该化合物的制备方法具有步骤少、操作简便、安全环保、收率高等优点，适合
Bibliography:Application Number: WO2015CN90291