USE OF ONE OR MORE ANTIMICROBIAL PEPTIDES TO INDUCE CELL DEATH IN VARIOUS TYPES OF CANCERS

The invention features methods and pharmaceutical compositions containing antimicrobial peptides (e.g. bactenecin) that can selectively interact with the cell surface of cancer cells to induce cell death. The methods and pharmaceutical compositions of the invention may be used to treat various cance...

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Bibliographic Details
Main Authors BOLKENT, SEHNAZ, SANCAR BAS, SERAP
Format Patent
LanguageEnglish
French
Published 23.06.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention features methods and pharmaceutical compositions containing antimicrobial peptides (e.g. bactenecin) that can selectively interact with the cell surface of cancer cells to induce cell death. The methods and pharmaceutical compositions of the invention may be used to treat various cancers, preferably, breast cancer. La présente invention concerne des procédés et des compositions pharmaceutiques contenant des peptides antimicrobiens (par exemple de la bacténécine) qui peut interagir de manière sélective avec la surface cellulaire de cellules cancéreuses afin d'induire une mort cellulaire. Les procédés et les compositions pharmaceutiques de l'invention peuvent être utilisés pour traiter divers cancers, de préférence un cancer du sein.
Bibliography:Application Number: WO2014TR00509