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Embodiments provided herein relate to methods and compositions for preparing an immobilized library of barcoded DNA fragments of a target nucleic acid, identifying genomic variants, determining the contiguity information, phasing information, and methylation status of the target nucleic acid. Des mo...

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Main Authors MEULEMAN, WOUTER, STEEMERS, FRANK J, NORBERG, STEVEN J, GUNDERSON, KEVIN L, HE, MOLLY, GORYSHIN, IGOR, IOANNOU, AVGOUSTA, BETLEY, JASON RICHARD, GORMLEY, NIALL ANTHONY, KIA, AMIRALI, MORRELL, NATALIE, JACKSON, ROSAMOND, PANTOJA, RIGO, POKHOLOK, DMITRY K, JENKINS, GARETH, WEIR, JACQUELINE, ZHANG, FAN
Format Patent
LanguageEnglish
French
Published 23.06.2016
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Embodiments provided herein relate to methods and compositions for preparing an immobilized library of barcoded DNA fragments of a target nucleic acid, identifying genomic variants, determining the contiguity information, phasing information, and methylation status of the target nucleic acid. Des modes de réalisation de la présente invention concernent des procédés et des compositions utilisés pour la préparation d'une bibliothèque immobilisée de fragments d'ADN à code à barres d'un acide nucléique cible, l'identification de variants génomiques, la détermination des informations de contiguïté, des informations de mise en phase, et de l'état de méthylation de l'acide nucléique cible.
Bibliography:Application Number: WO2015US56040