3-AMINO BENZAMIDE DERIVATIVE SERVING AS Β-LACTAM AUXILIARY ANTIBIOTIC, PREPARATION METHOD AND USE THEREOF

• Main Authors: CHEN, SHENG, YAP, HONG-KIN, CHIOU, JIAI, LUI, HOK-KIU, WONG, KWOK-YIN, KAN, JASON WING-YIU, CHAN, TAK-HANG, CHAN, KIN-FAI
• Format: Patent
• Language: Chinese; English; French
• Published: 17.03.2016
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A 3-amino benzamide derivative serving as a β-lactam auxiliary antibiotic, preparation method and use thereof; and the derivative is a compound of chemical formula (I), and can serve as a β-lactam auxiliary antibiotic to treat methicillin-resistant staphylococcal infections. L'invention concerne un dérivé de 3-amino benzamide servant d'antibiotique auxiliaire β-lactame, un procédé de préparation et une utilisation dudit dérivé; le dérivé étant un composé de formule chimique (I), et pouvant servir d'antibiotique auxiliaire β-lactame pour traiter des infections staphylococciques résistantes à la méthicilline. 一种作为β-内酰胺辅助抗生素的3-氨基苯甲酰胺衍生物、制备方法及应用，衍生物为化学式（I）的化合物。该衍生物能作为β-内酰胺辅助抗生素，用于治疗耐甲氧西林葡萄球菌感染。