CRYSTALLINE FORMS OF PALBOCICLIB

The present invention provides crystalline Form I, Form II, Form III, Form IV, Form V, Form V-A, Form VI, Form VII, and Form VIII of palbociclib, processes for their preparation, pharmaceutical compositions comprising these crystalline forms, and their use for the treatment of cyclin-dependent kinas...

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Main Authors SANGWAN, SANGEETA, THAIMATTAM, RAM, RAI, BISHWA, PRAKASH, ARYA, ANU, PRASAD, MOHAN, MOHAMMAD, KALLIMULLA
Format Patent
LanguageEnglish
French
Published 18.02.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides crystalline Form I, Form II, Form III, Form IV, Form V, Form V-A, Form VI, Form VII, and Form VIII of palbociclib, processes for their preparation, pharmaceutical compositions comprising these crystalline forms, and their use for the treatment of cyclin-dependent kinase associated diseases.5 La présente invention concerne la Forme I, la Forme II, la Forme III, la Forme IV, la Forme V, la Forme V-A, la Forme VI, la Forme VII et la Forme VIII cristallines de palbociclib, des procédés pour les préparer, des compositions pharmaceutiques comprenant ces formes cristallines, et leur utilisation pour le traitement de maladies associée à la kinase dépendante de la cycline.
Bibliography:Application Number: WO2015IB56187