COFORMER SALTS OF (2S,3S)-METHYL 7-FLUORO-2-(4-FLUOROPHENYL)-3-(1-METHYL-1H-1,2,4-TRIAZOL-5-YL)-4-OXO-1,2,3,4-TETRAHYDROQUINOLINE-5-CARBOXYLATE AND METHODS OF PREPARING THEM

• Main Authors: HERZ, CHRISTIAN, KLAUS, BONNAUD, THIERRY, LAMBERT, OLIVIER, JAGUSCH, CARSTEN, HENDERSON, MARK, BAUER, NICO, CAMPBELL, COLM
• Format: Patent
• Language: English; French
• Published: 04.02.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

Described herein are coformer salts of (2S,3S)-methyl 7-fluoro-2-(4-fluorophenyl)-3- ( 1-methyl- 1H- 1,2,4-triazol-5-yl)-4-oxo-l,2,3,4-tetrahydroquinoline-5-carboxylate optionally as a solvate and additionally optionally as a hydrate, including crystalline forms, and methods of preparing the (2S,3S)...